Effect of Glycyrrhizic Acid on Scopolamine-Induced Cognitive Impairment in Mice

  

Syzygium cumini fresh juice ameliorated memory impairment in a scopolamine-induced amnesic mouse model through active avoidance paradigm

Nosheen Malik, Hammad Murtaza, Waseem Ashraf, Muhammad Fawad Rasool, Farhan Siddique, Maryam Bashir, Tanveer Ahmad, Faleh Alqahtani, Imran Imran

Journal of Functional Foods.2025; 124: 106641.     CrossRef

Glycyrrhizic Acid Mitigates Haloperidol-Induced Neurotoxicity in SHSY-5Y Cells and Rats Via Activation of PI3k/Akt/Nrf2 Pathways

Mohammad Aqeel, Shubham Upadhayay, Ritika Devi, Kailash Jangid, Vinod Kumar, Puneet Kumar

Neurochemical Research.2025;[Epub]     CrossRef

The antioxidant role of aromatic plant extracts in managing neurodegenerative diseases: A comprehensive review

Youyang Zhu, Miao Tian, Shiyu Lu, Yuliang Qin, Ting Zhao, Hongling Shi, Zhaofu Li, Dongdong Qin

Brain Research Bulletin.2025; 222: 111253.     CrossRef

New findings on the antagonism of the environmental chemical toxicity 2-ethylhexyl diphenyl phosphate: Glycyrrhizic acid as an Nrf2 activator targets Nrf2/ROS/STAT3 signalling crosstalk to alleviate thymic injury in chicks

Linghuan Luo, Ming Ge, Yiming Sun, Yihan Hu, Xiaoyi Yang, Ruili Zhang

Poultry Science.2025; 104(4): 104918.     CrossRef

Evaluation of the Memory Enhancement Effects of Aminopyrimidine Derivatives Using the Scopolamine Model of Dementia in Mice

Behnaz Landi, Mona Khoramjouy, Alireza Ghavami Lahij, Sajjad Fazelkia, Salimeh Amidi, Farzad Kobarfard, Mehrdad Faizi

Neurotoxicity Research.2025;[Epub]     CrossRef

Neuroprotective effects of Petiveria alliacea on scopolamine-induced learning and memory impairment mouse model

Lizeth M. Zavala-Ocampo, Perla Y. López-Camacho, Eva Aguirre-Hernández, René Cárdenas-Vázquez, Herlinda Bonilla-Jaime, Gustavo Basurto-Islas

Journal of Ethnopharmacology.2024; 318: 116881.     CrossRef

A prospective review of the health-promoting potential of Jing Si Herbal Tea

Tsung-Jung Ho, Tanvir Ahmed, Marthandam Asokan Shibu, Yu-Jung Lin, Cheng Yen Shih, Pi-Yu Lin, Shinn-Zong Ling, Chien-Yi Chiang, Wei-Wen Kuo, Chih-Yang Huang

Tzu Chi Medical Journal.2024; 36(1): 1.     CrossRef

Glycyrrhizinic Acid and Phosphatidylcholine Combination as a Preventive Therapy for Experimental Murine Non-Alcoholic Steatohepatitis

Veronika A. Prikhodko, Tatyana M. Matuzok, Vadim E. Karev, Anna V. Karavaeva, Olga M. Spasenkova, Nadezhda V. Kirillova, Dmitry Yu. Ivkin, Sergey V. Okovityi

Livers.2024; 4(1): 63.     CrossRef

Glycyrrhizin functionalized CuS Nanoprobes for NIR Light-based therapeutic mitigation of acne vulgaris

Srivathsan Ganeshan, Nidhi Parihar, Donker Chonzom, Dinesh Mohanakrishnan, Rajdeep Das, Dandadhar Sarma, Devipriya Gogoi, Manash Ranjan Das, Suryanarayana Murty Upadhayula, Deepak Bharadwaj Pemmaraju

Drug Delivery and Translational Research.2024; 14(10): 2727.     CrossRef

Spectrum–effect relationship between HPLC fingerprints and antioxidant activity of Qi‐Fu‐Yin based on multiple statistical correlation analysis

Hengyu Li, Hongwei Zhao, Lingxiao Chen, Yong Yang, Shixue Wang, Rongyu Gao, Xiaorui Cheng

Phytochemical Analysis.2024; 35(7): 1565.     CrossRef

Neuroprotective Potential of Glycyrrhizic Acid in Ischemic Stroke: Mechanisms and Therapeutic Prospects

Yanwen Li, Juan Wu, Fang Du, Tao Tang, Jonathan Chee Woei Lim, Thilakavathy Karuppiah, Jiaxin Liu, Zhong Sun

Pharmaceuticals.2024; 17(11): 1493.     CrossRef

The therapeutic potential of glycyrrhizic acid and its metabolites in neurodegenerative diseases: Evidence from animal models

Xiansi Zeng, Zixuan Sheng, Yuqian Zhang, Jing Xiao, Yang Li, Jiaping Zhang, Guangtao Xu, Jinjing Jia, Min Wang, Li Li

European Journal of Pharmacology.2024; 985: 177098.     CrossRef

A Systematic Review Investigating the Impact of Glycyrrhiza glabra on Cognitive Function and Memory: A Comprehensive Analysis

Mrudul Y. Chitrakar, Vinay Pawar, Mangala Wange, Vedvati K. Bhapkar

Journal of Natural Remedies.2024; : 2667.     CrossRef

Mechanistic insights into monomer level prevention of amyloid aggregation of lysozyme by glycyrrhizic acid

Shivani A. Muthu, Rahul Sharma, Afnaan Qureshi, Suhel Parvez, Basir Ahmad

International Journal of Biological Macromolecules.2023; 227: 884.     CrossRef

Ganmaidazao decoction alleviated cognitive impairment on Alzheimer's disease rats by regulating gut microbiota and their corresponding metabolites

Meirong Cui, Xiao Shan, Yumeng Yan, Tiantian Zhao, Yue Sun, Wenqian Hao, Ziwei Wang, Yafei Chang, Yao Xie, Binbin Wei

Arabian Journal of Chemistry.2023; 16(5): 104688.     CrossRef

Investigation of the protective effect of long-term exercise on molecular pathways and behaviours in scopolamine induced alzheimer's disease-like condition

Seda Kose, Meltem Donmez Kutlu, Samet Kara, Sait Polat, Kubra Akillioglu

Brain Research.2023; 1814: 148429.     CrossRef

Anti‐oomycete ability of scopolamine against Phytophthora infestans, a terrible pathogen of potato late blight

Zhiming Zhu, Ziwen Xiong, Wenjin Zou, Zhiwen Shi, Shanying Li, Xinze Zhang, Shicheng Liu, Yi Liu, Xunguang Luo, Jie Ren, Zhenglin Zhu, Pan Dong

Journal of the Science of Food and Agriculture.2023; 103(13): 6416.     CrossRef

Neuroprotective effect of total flavonoids in stems and leaves of Glycyrrhiza uralensis Fisch. on oxidative stress in HT-22 cells and Caenorhabditis elegans

Weijia Chen, Lei He, Hongyan Pei, Jianming Li, Yan Zhao, Ying Zong, Hong Kan, Zhongmei He, Rui Du

Aging.2023;[Epub]     CrossRef

Serum lipidomics reveal the mechanism of memory disorder improvement by Qifu decoction

Fanying Deng, Fuxia Zhao, Wenhui Wang, Shiqi Liu, Yan Wang

Analytical Methods.2023; 15(36): 4663.     CrossRef

Recent Advances in the Pharmacological Activities of Glycyrrhizin, Glycyrrhetinic Acid, and Their Analogs

Ankit Mittal, Mudita Nagpal, Vinod Kumar Vashistha

Revista Brasileira de Farmacognosia.2023; 33(6): 1154.     CrossRef

Unlocking the Therapeutic Potential of Medicinal Plants for Alzheimer’s Disease: Preclinical to Clinical Trial Insights

Kushagra Nagori, Kartik T. Nakhate, Krishna Yadav, Ajazuddin, Madhulika Pradhan

Future Pharmacology.2023; 3(4): 877.     CrossRef

Long term effect of fluoxetine and memantine on biochemical markers of Alzheimer’s disease in scopolamine-induced mice

N. N. H. Istifo, M. A. J. Al-Zobaidy, K. S. Abass

Regulatory Mechanisms in Biosystems.2023; 15(2): 226.     CrossRef

A new arylsulfanyl-benzo-2,1,3-thiadiazoles derivative produces an anti-amnesic effect in mice by modulating acetylcholinesterase activity

Karline da Costa Rodrigues, Renata Leivas de Oliveira, Julia da Silva Chaves, Vanessa Macedo Esteves da Rocha, Beatriz Fuzinato dos Santos, Mariana Gallio Fronza, Nelson Luís de Campos Domingues, Lucielli Savegnago, Ethel Antunes Wilhelm, Cristiane Luches

Chemico-Biological Interactions.2022; 351: 109736.     CrossRef

Traditional Chinese Medicine as a Promising Strategy for the Treatment of Alzheimer’s Disease Complicated With Osteoporosis

Weifan Xu, Yiping Jiang, Nani Wang, Huanhuan Bai, Shengyan Xu, Tianshuang Xia, Hailiang Xin

Frontiers in Pharmacology.2022;[Epub]     CrossRef

Tropane alkaloids (hyoscyamine, scopolamine and atropine) from genus Datura: extractions, contents, syntheses and effects

Zhiwen Shi, Wenjin Zou, Zhiming Zhu, Ziwen Xiong, Shanying Li, Pan Dong, Zhenglin Zhu

Industrial Crops and Products.2022; 186: 115283.     CrossRef

Friedelin Attenuates Neuronal Dysfunction and Memory Impairment by Inhibition of the Activated JNK/NF-κB Signalling Pathway in Scopolamine-Induced Mice Model of Neurodegeneration

Marva Sandhu, Hafiz Muhammad Irfan, Shahid Ali Shah, Madiha Ahmed, Iffat Naz, Muhammad Akram, Humaira Fatima, Ayesha Shuja Farooq

Molecules.2022; 27(14): 4513.     CrossRef

Efficacy of diammonium glycyrrhizinate in the treatment of rosacea with papules and pustules: A randomized, double‐blind, placebo‐controlled study

Yuming Xie, Junke Huang, Juan Liu, Qing Zhang

Dermatologic Therapy.2022;[Epub]     CrossRef

Investigation of the Protective Effect of Long-Term Exercise on Molecular Pathways and Cognitive Behaviors in Alzheimer Disease Model

seda kose, Meltem Donmez Kutlu, Samet Kara, Sait Polat, Kubra Akillioglu

SSRN Electronic Journal.2022;[Epub]     CrossRef

RETRACTED ARTICLE: Atrazine-induced cell-mediated immunotoxicity in rabbits and the ameliorating role of glycyrrhizic acid

Mona K. Galal, Ashraf M. Morgan, Marwa A. Ibrahim, Ahmed M. Hussien

Environmental Science and Pollution Research.2021; 28(24): 32027.     CrossRef

Shenzhiling oral solution promotes myelin repair through PI3K/Akt-mTOR pathway in STZ-induced SAD mice

Gaofeng Qin, Yahan Wang, Zhenhong Liu, Lulu Mana, Shuaiyang Huang, Pengwen Wang

3 Biotech.2021;[Epub]     CrossRef

Targeting Mitochondrial Biogenesis with Polyphenol Compounds

Leila Chodari, Mutlu Dilsiz Aytemir, Parviz Vahedi, Mahdieh Alipour, Sepideh Zununi Vahed, Seyed Mahdi Hosseiniyan Khatibi, Elham Ahmadian, Mohammadreza Ardalan, Aziz Eftekhari, Felipe L. de Oliveira

Oxidative Medicine and Cellular Longevity.2021;[Epub]     CrossRef

Perilla Frutescens Extract Protects against Scopolamine-Induced Memory Deficits in Mice

Jihye Lee, Eunhong Lee, Eun Mi Jung, Dong Hyun Kim, Sung-kyu Kim, Mi Hee Park, Ji Wook Jung

Journal of Physiology & Pathology in Korean Medicine.2021; 35(3): 97.     CrossRef