International Neurourology Journal (INJ)

The pharmacological effects of Berberine and its therapeutic potential in different diseases: Role of the phosphatidylinositol 3‐kinase/AKT signaling pathway

Mohammad Rafi Khezri, Somayeh Mohammadipanah, Morteza Ghasemnejad‐Berenji

The mechanism of microglia-mediated immune inflammation in ischemic stroke and the role of natural botanical components in regulating microglia: A review

Jinsong Zeng, Tingting Bao, Kailin Yang, Xiaofei Zhu, Shanshan Wang, Wang Xiang, Anqi Ge, Liuting Zeng, Jinwen Ge

Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials

Lele Yang, Wenyu Zhu, Xiaobo Zhang, Xin Zhou, Wenbin Wu, Tao Shen

Regulatory mechanisms of natural compounds from traditional Chinese herbal medicines on the microglial response in ischemic stroke

Myong Hak Ri, Yue Xing, Hong Xiang Zuo, Ming Yue Li, Hong Lan Jin, Juan Ma, Xuejun Jin

Palmatine, a natural alkaloid, attenuates memory deficits and neuroinflammation in mice submitted to permanent focal cerebral ischemia

Juliana Fernandes Pereira, Juliana Catharina de Sousa Neves, Analu Aragão Fonteles, Jéssica Rabelo Bezerra, Rayssa Costa Pires, Ana Thais Araújo da Silva, Francisco Arnaldo Viana Lima, Kelly Rose Tavares Neves, Reinaldo Barreto Oriá, Glauce Socorro de Bar

Journal of Neuroimmunology.2023; 381: 578131. CrossRef

Demethyleneberberine, a potential therapeutic agent in neurodegenerative disorders: a proposed mechanistic insight

Priyanka Saklani, Heena Khan, Thakur Gurjeet Singh, Saurabh Gupta, Amarjot Kaur Grewal

Molecular Biology Reports.2022; 49(10): 10101. CrossRef

Can Berberine Serve as a New Therapy for Parkinson’s Disease?

Ehsan Dadgostar, Mahsa Moghanlou, Mehrnoosh Parvaresh, Salimeh Mohammadi, Mohammadali Khandan, Michael Aschner, Hamed Mirzaei, Omid Reza Tamtaji

Neurotoxicity Research.2022; 40(4): 1096. CrossRef

Expatiating the Pharmacological and Nanotechnological Aspects of the Alkaloidal Drug Berberine: Current and Future Trends

Tapan Behl, Sukhbir Singh, Neelam Sharma, Ishrat Zahoor, Ali Albarrati, Mohammed Albratty, Abdulkarim M. Meraya, Asim Najmi, Simona Bungau

Phytochemicals as regulators of microglia/macrophages activation in cerebral ischemia

Pharmacological Research.2021; 165: 105419. CrossRef

Neuroprotective Phytochemicals in Experimental Ischemic Stroke: Mechanisms and Potential Clinical Applications

Hui Xu, Emily Wang, Feng Chen, Jianbo Xiao, Mingfu Wang, Daniele Vergara

Oxidative Medicine and Cellular Longevity.2021; 2021: 1. CrossRef

Natural products attenuate PI3K/Akt/mTOR signaling pathway: A promising strategy in regulating neurodegeneration

Sajad Fakhri, Amin Iranpanah, Mohammad Mehdi Gravandi, Seyed Zachariah Moradi, Mohammad Ranjbari, Mohammad Bagher Majnooni, Javier Echeverría, Yaping Qi, Mingfu Wang, Pan Liao, Mohammad Hosein Farzaei, Jianbo Xiao

Berberine ameliorates testosterone-induced benign prostate hyperplasia in rats

Ehsan Shabani, Heibatullah Kalantari, Mojtaba Kalantar, Mehdi Goudarzi, Esrafil Mansouri, Hadi Kalantar

BMC Complementary Medicine and Therapies.2021;[Epub] CrossRef

Angelica sinensis extract protects against ischemia-reperfusion injury in the hippocampus by activating p38 MAPK-mediated p90RSK/p-Bad and p90RSK/CREB/BDNF signaling after transient global cerebral ischemia in rats

Journal of Ethnopharmacology.2020; 252: 112612. CrossRef

Berberine hydrochloride mitigates acute pancreatitis by suppressing the TLR4/IκBα/NFκB pathway

Huali Gu, Aiguo Liu, Weiping Ma, Jianmin Ni, Chengtai Ma, Xiumei Zhou, Zhenfang Liu, Di Xia, Xintao Tian, Lei Shi, Liang Zhu

Goldenseal (Hydrastis canadensis L.) and its active constituents: A critical review of their efficacy and toxicological issues

Sudip Kumar Mandal, Amal Kumar Maji, Siddhartha Kumar Mishra, Pir Mohammad Ishfaq, Hari Prasad Devkota, Ana Sanches Silva, Niranjan Das

Pharmacological Research.2020; 160: 105085. CrossRef

Effects of rosmarinic acid on nervous system disorders: an updated review

Mahboobeh Ghasemzadeh Rahbardar, Hossein Hosseinzadeh

Naunyn-Schmiedeberg's Archives of Pharmacology.2020; 393(10): 1779. CrossRef

Neuroprotective role of polyphenols against oxidative stress-mediated neurodegeneration

Md. Sahab Uddin, Abdullah Al Mamun, Md. Tanvir Kabir, Jamil Ahmad, Philippe Jeandet, Md. Shahid Sarwar, Ghulam Md Ashraf, Lotfi Aleya

European Journal of Pharmacology.2020; 886: 173412. CrossRef

AMPK and its Activator Berberine in the Treatment of Neurodegenerative Diseases

Siru Qin, Huiling Tang, Wei Li, Yinan Gong, Shanshan Li, Jin Huang, Yuxin Fang, Wenjuan Yuan, Yangyang Liu, Shenjun Wang, Yongming Guo, Yi Guo, Zhifang Xu

Current Pharmaceutical Design.2020; 26(39): 5054. CrossRef

Protective effects of berberine hydrochloride on DSS-induced ulcerative colitis in rats

International Immunopharmacology.2019; 68: 242. CrossRef

Combating Neurodegenerative Diseases with the Plant Alkaloid Berberine: Molecular Mechanisms and Therapeutic Potential

Current Neuropharmacology.2019; 17(6): 563. CrossRef

Berberine Ameliorates Brain Inflammation in Poloxamer 407-Induced Hyperlipidemic Rats

Mia Kim, Tae-Woon Kim, Chang-Ju Kim, Mal-Soon Shin, Minha Hong, Hye-Sang Park, Sang-Seo Park

International Neurourology Journal.2019; 23(Suppl 2): S102. CrossRef

Berberine: A Plant-derived Alkaloid with Therapeutic Potential to Combat Alzheimer’s disease

Anurag K. Singh, Santosh K. Singh, Manmath K. Nandi, Gaurav Mishra, Anand Maurya, Arati Rai, Gopal K. Rai, Rajendra Awasthi, Bhupesh Sharma, Giriraj T. Kulkarni

Central Nervous System Agents in Medicinal Chemistry .2019; 19(3): 154. CrossRef

Effects of Berberine chloride on the liver of streptozotocin-induced diabetes in albino Wistar rats

Govindasami Chandirasegaran, Chakkaravarthy Elanchezhiyan, Kavisa Ghosh

Biomedicine & Pharmacotherapy.2018; 99: 227. CrossRef

Anti-Inflammatory Effects of Berberine Hydrochloride in an LPS-Induced Murine Model of Mastitis

Xichun Wang, Shibin Feng, Nana Ding, Yanting He, Cheng Li, Manman Li, Xuedong Ding, Hongyan Ding, Jinchun Li, Jinjie Wu, Yu Li

Evidence-Based Complementary and Alternative Medicine.2018; 2018: 1. CrossRef

Phytotherapy Research.2018; 32(8): 1501. CrossRef

Neuroprotective effect of vildagliptin against cerebral ischemia in rats

Salma A. El-Marasy, Rehab F. Abdel-Rahman, Reham M. Abd-Elsalam

Naunyn-Schmiedeberg's Archives of Pharmacology.2018; 391(10): 1133. CrossRef

Bharath Velmurugan, Baskaran Rathinasamy, Bharathi Lohanathan, Varadharajan Thiyagarajan, Ching-Feng Weng

Berberine ameliorates neonatal necrotizing enterocolitis by activating the phosphoinositide 3-kinase/protein kinase B signaling pathway

Chengzhi Fang, Lili Xie, Chunmei Liu, Chunhua Fu, Wei Ye, Hong Liu, Binghong Zhang

Experimental and Therapeutic Medicine.2018;[Epub] CrossRef

Effect of treadmill exercise on spatial navigation impairment associated with cerebellar Purkinje cell loss following chronic cerebral hypoperfusion

Jae‑Min Lee, Chang‑Ju Kim, Jong‑Min Park, Min Song, Youn‑Jung Kim

RETRACTED: Rosmarinic acid protects rat hippocampal neurons from cerebral ischemia/reperfusion injury via the Akt/JNK3/caspase-3 signaling pathway

Hepatoprotective Effects of Corilagin Following Hemorrhagic Shock are Through Akt-Dependent Pathway

Repetitive Transcranial Magnetic Stimulation Ameliorates Cognitive Impairment by Enhancing Neurogenesis and Suppressing Apoptosis in the Hippocampus in Rats with Ischemic Stroke

Feng Guo, Jicheng Lou, Xiaohua Han, Yuguo Deng, Xiaolin Huang

Berberine chloride ameliorates oxidative stress, inflammation and apoptosis in the pancreas of Streptozotocin induced diabetic rats

Govindasami Chandirasegaran, Chakkaravarthy Elanchezhiyan, Kavisa Ghosh, Subramaniam Sethupathy

Biomedicine & Pharmacotherapy.2017; 95: 175. CrossRef

Berberine attenuated pro-inflammatory factors and protect against neuronal damage via triggering oligodendrocyte autophagy in spinal cord injury

Hongyu Wang, Chang Liu, Xifan Mei, Yang Cao, Zhanpeng Guo, Yajiang Yuan, Ziming Zhao, Changwei Song, Yue Guo, Zhaoliang Shen

Berberine inhibits the ischemia‑reperfusion injury induced inflammatory response and apoptosis of myocardial cells through the phosphoinositide 3‑kinase/RAC‑α serine/threonine‑protein kinase and nuclear factor-κB signaling pathways

Lixin Wang, Hao Ma, Yan Xue, Haiyan Shi, Teng Ma, Xiaozheng Cui

Experimental and Therapeutic Medicine.2017;[Epub] CrossRef

Berberine protects against light-induced photoreceptor degeneration in the mouse retina

Delu Song, Jiantao Song, Chenguang Wang, Yafeng Li, Joshua L. Dunaief

PI3K/Akt pathway contributes to neuroprotective effect of Tongxinluo against focal cerebral ischemia and reperfusion injury in rats

Zhong-Hai Yu, Min Cai, Jun Xiang, Zhen-Nian Zhang, Jing-Si Zhang, Xiao-Ling Song, Wen Zhang, Jie Bao, Wen-Wei Li, Ding-Fang Cai

Journal of Ethnopharmacology.2016; 181: 8. CrossRef

Cardiac-protective effects and the possible mechanisms of alatamine during acute myocardial ischemia

Chengguo Zhao, Fanxin Meng, Lulu Geng, Xi Zhao, Hui Zhou, Yao Zhang, Shuzhi Qin

Canadian Journal of Physiology and Pharmacology.2016; 94(4): 433. CrossRef

Pentoxifylline Alleviates Perinatal Hypoxic-Ischemia-Induced Short-term Memory Impairment by Suppressing Apoptosis in the Hippocampus of Rat Pups

Je Hoon Park, Sung Eun Kim, Jun Jang Jin, Han Sung Choi, Chang Ju Kim, Il Gyu Ko

International Neurourology Journal.2016; 20(2): 107. CrossRef

Neuroprotective Effect of Salvianolic Acids against Cerebral Ischemia/Reperfusion Injury

Shuai Hou, Ming-Ming Zhao, Ping-Ping Shen, Xiu-Ping Liu, Yuan Sun, Jia-Chun Feng

International Journal of Molecular Sciences.2016; 17(7): 1190. CrossRef

Berberis Vulgaris and Berberine: An Update Review

Phytotherapy Research.2016; 30(11): 1745. CrossRef

Therapeutic Potential and Mechanisms of Berberine in Cardiovascular Disease

Current Pharmacology Reports.2016; 2(6): 281. CrossRef

Treadmill Exercise Improves Memory Function Depending on Circadian Rhythm Changes in Mice

Dong Sup Hwang, Hyo Bum Kwak, Il Gyu Ko, Sung Eun Kim, Jun Jang Jin, Eun Sang Ji, Hyun Hee Choi, Oh Young Kwon

International Neurourology Journal.2016; 20(Suppl 2): S141. CrossRef

Functional study of the upregulation of miRNA-27a and miRNA-27b in 3T3-L1 cells in response to berberine

Yue-Yue Wu, Xin-Mei Huang, Jun Liu, Ying Cha, Zao-Ping Chen, Fang Wang, Jiong Xu, Li Sheng, He-Yuang Ding

Molecular Medicine Reports.2016; 14(3): 2725. CrossRef

Postnatal treadmill exercise attenuates prenatal stress-induced apoptosis through enhancing serotonin expression in aged-offspring rats

Tae-Woon Kim, Eun-Sang Ji, Tae-Wook Kim, Sang-Won Lee, Choong-Yeol Lee, Sam-Jun Lee

Journal of Exercise Rehabilitation.2015; 11(1): 12. CrossRef

Berberine is a dopamine D1- and D2-like receptor antagonist and ameliorates experimentally induced colitis by suppressing innate and adaptive immune responses

Masaaki Kawano, Rie Takagi, Atsushi Kaneko, Sho Matsushita

Journal of Neuroimmunology.2015; 289: 43. CrossRef

Therapeutic Effect of Berberine on Huntington’s Disease Transgenic Mouse Model

Wenxiao Jiang, Wenjie Wei, Marta A. Gaertig, Shihua Li, Xiao-Jiang Li, Huaibin Cai

Neurourology Transforms the Drug Development Experience

International Neurourology Journal.2014; 18(3): 105. CrossRef