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Int Neurourol J > Volume 16(2); 2012 > Article
Oh, Son, Kim, Lee, Choo, Kim, and Lee: Psychometric Properties of the Korean Version of the Overactive Bladder Questionnaire (OAB-q) in a Korean Population



Psychometric properties of the overactive bladder questionnaire (OAB-q) were recently examined. However, since the cross-cultural adaptation of a non-English version of the OAB-q has never been demonstrated, we evaluated the psychometric properties of a Korean version of the OAB-q in a Korean population with OAB.


A prospective cohort study involving 116 women with 58 OAB and 58 control subjects was performed and convergent validity was assessed. Total and subscale OAB-q scores of the control and OAB groups were compared to their sensitivity to score changes before and after administering anti-cholinergic medication for 12 weeks. Short form 36 and King's health questionnaire (KHQ) were also used for comparison or correlation.


Assessment of face validity showed that the Korean version of the OAB-q was reasonable with OAB-q subscale scores being significantly different between the control and patient groups. Significant correlation (range, -0.29 to -0.81) was found between the OAB-q scores and KHQ results for the OAB patients. Cronbach's alpha coefficients (range, 0.77 to 0.95) indicated excellent internal consistency and test-retest analysis involving 35 OAB patients showed that each questions as well as subscale scores were reproducible. Each score of OAB-q also showed statistically significant sensitivity to changes following anti-muscarinic treatment for OAB (n=27, P<0.001 except for social, P=0.059).


The Korean version of the OAB-q is a valid and reliable instrument to measure outcomes in Korean patients with OAB.



    Overactive bladder (OAB) is characterized by symptoms of urinary urgency which may be accompanied by urge incontinence, increased urination frequency, and/or nocturia [1]. The overall prevalence of chronic and debilitating OAB symptoms in six European countries is 16.6% [2]. In the United States (US), the prevalence of OAB is very similar to that in Europe, with 16.0% in men and 16.9% in women suffering from this condition [3]. The estimated total economic cost of OAB is over 12 billion dollars in 2000 in the US alone [4].
    OAB has been shown to cause significant symptom burden and impairs health-related quality of life (HRQoL) by interfering with daily activities, travel, sleep, and personal relationships [5-8]. Among the many questionnaires available for evaluating lower urinary symptoms, the King's health questionnaire (KHQ) [9,10], OAB questionnaire (OAB-q) [7,11,12] and OAB symptom score [13,14] have been validated for clinical use in a sample of incontinent OAB patients. The OAB-q was developed by Coyne et al. [7] in the US. It consists of 33 self-administered questions, eight which involve a symptom-bother scale and 25 involving HRQoL scores that constitute four subscales measuring coping, concern, sleep, and social interaction. The OAB-q questions are simple and easy to answer. Two subset of the OAB-q, the OAB-q short form (SF) and screening tool (OAB-q V8), were derived from the original OAB-q. The OAB-q SF was developed by selecting six items from the original eight symptom-bother items and 13 items from the original 25 HRQoL items. The OAB-q V8 consists of the first eight OAB-q questions. Patients rate each item using a six-point Likert scale ranging from 'none of the time' to 'all of the time' for the HRQoL items and 'not at all' to 'a very great deal' for the symptom-bother items. Therefore, higher symptom severity score values are indicative of greater symptom severity or bother, whereas higher HRQoL scores are indicative of better HRQoL [7]. Subscale responses are summed and converted into scores ranging from 0 to 100.
    Evaluation of the psychometric properties was performed and demonstrated that the concurrent validity and discriminant validity [7], test-retest [11], and responsiveness [12] of the US English version of the OAB-q are acceptable. This questionnaire was translated into 14 different languages including French, German, Italian, Danish, and Korean [15]. To use the translated questionnaire in clinical practice as well as for clinical research, the psychometric properties of the translated versions should be accurately validated. Full validation and cross-cultural adaptation of the non-English version of the OAB-q has been performed in Danish, German, Polish, Swedish, and Turkish [16]. The primary objective of this study was to investigate whether the Korean version of the OAB-q provides valid and reliable information on Korean patients with OAB.


    This study was a prospective multi-center cohort study involving Seoul National University Hospital (SNUH) and SMG-SNU Boramae Medical Center (Seoul, Korea) which is an affiliated of SNUH. Participants were recruited from individual urology clinics and the study protocol was approved by the Institutional Review Boards of SNUH (H-0610-035-187).
    Patients willing to participate in the study were recruited based on specific criteria with the definition of OAB used in this study followed the recent standardized terminology of the International Continence Society [1]. The diagnosis of OAB was based primarily on the investigators' assessment of the participant's history during the first visit. Inclusion criteria were: 1) OAB symptoms for at least 6 months, 2) ages greater than 18 years old, 3) not currently taking medication for OAB symptoms, 4) not pregnant or nursing, and 5) absence of an acute urinary tract infection. Exclusion criteria were: 1) predominant stress urinary incontinence, 2) an indwelling catheter or intermittent catheterization, 3) symptoms of or recurrent urinary tract infection, 4) bladder cancer, 5) hepatic or renal dysfunction, 6) diabetic neuropathy, 7) congenital urological disorders, 8) undergoing electrostimulation, bladder training, or pelvic floor exercise within 4 weeks of study entry, and 9) pregnancy. Individuals who were less than 18 years old or who do not read and write were also excluded. Overall, 58 patients were enrolled in the OAB group. To assess the OAB-q responsiveness, a total of 35 out of 58 OAB patients were given anticholinergic medication for 3 months. A total of 104 women with each group sample sizes of 52 was needed to achieve 80% power detecting a difference of 11.0 between the two groups with known group standard deviations of 20.0 and with a significance level (alpha) of 0.05. Therefore, a total of 116 women with 58 subjects in each group were enrolled, considering follow-up loss rate of 15%. A total of 35 subjects were enrolled for test-retest analysis, considering follow-up loss rate of 15%. These 35 patients were included in the original cohort of 116 women.
    The inclusion criteria for the control group (n=58) were: 1) an absence of major chronic and acute disease, 2) no history of treatment for lower urinary tract symptoms, and 3) no subjective complaints of voiding symptoms. Exclusion criteria were being treated for urological conditions including stress urinary incontinence and urinary tract infection. In summary, asymptomatic subjects with no or mild voiding symptoms visiting the Health Promotion Center in SNUH for a routine health check-up were selected for the control group.
    After receiving information about the purpose and nature of the study, all participants of OAB group and control group provided written informed consent. Clinical and demographic data were collected from all participants. The OAB group then completed questions for the face validity, Korean version of the OAB-q, a fully-validated Korean version of the KHQ, and Medical Outcomes Study SF-36 which is well-known as a typical type of generic non-disease specific questionnaire to assess HRQoL. The control group completed the OAB-q, KHQ, and SF-36. The permission for use of afore-mentioned questionnaires for this study was obtained from each copyright holder.


    To assess face and content validity, questions were adopted from our previous study that validated the Korean version of the KHQ [17,18]. A descriptive analysis was performed for each question. The ability of the OAB-q to discriminate OAB patients from individuals in the control group was examined by comparing tertiles of the baseline OAB-q scores. Clinical indicators including KHQ and SF-36 scores were also compared between the two groups. Wilcoxon rank sums test was used to determine whether scores of the OAB patients were significantly different from those of the control group. Convergent validation involved comparing the OAB-q total score as well as the four subscale scores with appropriately related measures including the KHQ and SF-36 scores using Spearman's correlation coefficients.


    Internal consistency of the Korean OAB-q was assessed by calculating Cronbach's coefficient. After the first surveys were completed, the participants were offered the same questionnaire 2 weeks later to demonstrate reproducibility. We expected that the 2-week interval was a sufficient amount of time for respondents to forget their original answers but not long enough for any OAB symptoms to dramatically change. Test-retest reliability was assessed using the intra-class correlation coefficient, which is derived from an analysis of variance, and Spearman's correlation. Spearman's correlation coefficients were classified as small (0.10), moderate (0.30), or large (0.50).


    Responsiveness is the ability of an instrument to detect small but important changes. The OAB group was given tolterodine SR (4 mg per day) or other comparable anticholinergic agents for 12 weeks to evaluate sensitivity of the OAB-q to symptom change. Patients completed the OAB-q before and after 12 weeks of treatment. Responsiveness was analyzed by calculating the differences in the Korean OAB-q scores before and after treatment using Wilcoxon signed rank test. Effect sizes of the OAB-q were calculated by dividing the difference in mean scores from baseline to week 12 by the standard deviation of the baseline scores. Effect size was classified as small (0.20), moderate (0.50), or large (0.80). The standardized response mean was calculated by dividing the difference in mean scores before and after treatment by the standard deviation of this difference.

    Statistical Analysis

    All statistical analyses were independently performed using SAS Ver. 18.0 (SAS Institute Inc., Cary, NC, USA) by biostatisticians (SOK, MSL). Patient characteristics were expressed as mean±SD for continuous variables and as N and percentages for categorical variables. Any questionnaires with missing items were excluded from the analysis. If ≤50% of the scale items were missing in the subscale analysis, the scale was retained and the mean scale score of the items present were used to impute a score for the missing items. If >50% of the items was missing, no scale scores were calculated and were considered to be missing [7]. If subscales score were missing, the HRQoL total score was not calculated.


    Readability and Acceptability

    Demographic and clinical characteristics of the patients are summarized in Table 1. The mean age was 62.7 (±10.2, SD) years. Assessment of face validity showed that the Korean version of the OAB-q was acceptable (Table 2). 81.0% of the patients said that time taken to complete answering the questionnaire were within 20 minutes and 84.4% stated that each question was simple and easy to understand. The participants thought that most items of the OAB-q were relevant, each question was clearly worded and easily understood, and the format of the questionnaire was acceptable.


    Discriminant validity

    Significant differences were noted between the scores for the control and OAB groups. All OAB-q and OAB-q SF subscales showed sufficient discriminate validity (P<0.001) (Table 3). There were also significant differences between the two groups in all KHQ subscales. Significant differences were also consistently noted between the control and OAB groups in most SF-36 domains (P<0.05).

    Convergent validity

    Compared to OAB-related measures (Table 4), the OAB-q subscales moderately correlated with the KHQ subscales (P<0.05). Convergent validity was acceptable with high correlation coefficients among conceptually-related domains. Domains related to limitations of daily life including physical limitations, social limitations, and sleep/energy in the KHQ showed high correlations with the OAB-q domains. However, correlations between the OAB-q scores and SF-36 of the OAB patients were relatively weak compared to other inter-domain correlations (e.g., in OAB-q HRQoL total, 0.010 with SF-36 mental health, 0.065 with SF-36 pain). These results indicate low discriminant validity with relatively weak correlation among conceptually unrelated domains.


    Internal consistency

    Cronbach's alpha coefficients (>0.82) indicated excellent internal consistency (Table 5). The OAB-q SF HRQoL was found to have high internal consistency according to the Cronbach's alpha coefficient (0.90).


    Test-retest analysis showed that each item as well as subscale scores were reproducible (Table 6). Interclass correlation coefficients for domains of the OAB-q subscales and SF ranged from 0.55 to 0.77 (P<0.001 for all). Spearman's correlations for the OAB-q HRQoL (0.69) and OAB-q SF HRQoL indicated a strong association between participant responses during the first and second visit (P<0.001). Analysis of each OAB-q item indicated that the responses between the two visits remained consistent.


    Change in scores before and after treatment

    A total of 35 OAB patients started anticholinergic medication and 27 patients were followed-up. The OAB-q scales, except those for the social and OAB-q SF, exhibited significant change (P<0.001) (Table 7). Treatment also led to significant changes in all KHQ scores except for ones associated with Personal Relationships (P<0.05).

    Effect size and standardized response mean

    Results indicating the effect size and response mean for the OAB-q scales from baseline to week 12 of treatment are shown in Table 7. The effect sizes of the OAB-q subscales from baseline to week 12 ranged from 0.57 to 1.48. All subscales except the social subscale showed large effect sizes. Results for the standardized response mean were similar to those of the effect sizes.


    OAB is defined by symptoms. For symptoms based on pathological conditions, HRQoL is considered to be a key factor for evaluating intervention effects. Therefore, critical quantification of a patient's symptoms is an absolute necessity for analyzing baseline symptomatic distress and assessing changes in distress and HRQoL in response to drug therapy and/or surgery. One of the most widely used questionnaires for patients with urinary incontinence is the KHQ. This questionnaire was translated into Korean and the linguistic accuracy was validated by our team [17]. Subsequent full-scale psychometric evaluation was also performed, proving that the KHQ is a valid and reliable tool for assessing female patients with stress urinary incontinence [18]. The KHQ is commonly used to assess urge incontinence. However, it was not developed to specifically examine conditions associated with OAB. A more direct comparison between the KHQ and OAB-q has not been performed although it is generally assumed that the OAB-q, which is a condition-specific questionnaire, is superior to more generic questionnaires.
    Some Korean patients and physicians have reported that the original Korean version of the OAB-q (ver. 1.0) is difficult to understand. These individuals pointed out that some parts of the sentences were confusing because they were directly translated from English into Korean. Since the final validated version has may be widely used by both Korean patients and physicians, we felt that a revision was necessary. Prior to starting the psychometric validation, the Korean OAB-q underwent another linguistic review by our research team including back translation, forward translation, reconciliation, and debriefing patient interview. Thorough review of the new version was performed and expert opinion of the revised version was obtained from leading urologists who were involved in creating the first version of the Korean OAB-q. Finally, 11 minor revisions were made in the final Korean version 2.0 based on a comparison to the original version (the process was completed on June 26, 2007). The revised version (2.0) of the Korean OAB-q was then psychometrically validated.
    In the present study, full-scale psychometric properties including content/face validity, discriminant validity, convergent validity, internal consistency, test-retest analysis, and responsiveness of the Korean OAB-q were evaluated in a Korean population. The OAB-q and OAB-q SF was validated using two distinct groups, control and patients. The results varied according to these two groups, thus providing evidence of discriminant validity. There were also significant differences in the KHQ subscales except for the one that assessed personal relationships.
    The SF-36 has been used extensively as an indicator of HRQoL, and its reliability and validity are well-documented [19]. However, our convergent validity study showed that correlations between the OAB-q scores and SF-36 in OAB patients were relatively weak. This might be because SF-36 is a generic questionnaire rather than a disease-specific one. Our previous study demonstrated that a generic QoL questionnaire is not a sensitive tool for measuring QoL in patients with urinary incontinence compared to more condition-specific [20]. Our test-retest analysis showed that the scores for each item and subscales were highly reproducible. Correlation analyses revealed a strong association between the OAB-q scores recorded during the first and second visits. Cronbach's alpha coefficients also indicated excellent internal consistency. The usefulness of measuring outcomes based on self-reporting methods depends not only on the validity and reliability of the technique, but also on the ability to detect treatment-related changes over time. The effect size and standardized response mean from baseline to week 12 of treatment observed in this study showed that the OAB-q is a very sensitive tool for detecting relatively small subjective symptomatic changes that occurred between two visits.
    A potential limitation of this study exists as all our subjects were female. There still lies a need to validate the Korean version of the OAB-q in the male population in the future, given that the OAB affects both sexes. In addition we would also like to validate OAB patients of neurologic disease with coming revisions to our study. There is a growing need for fully validated OAB questionnaires in various languages for multinational clinical trials. Our results showed that full validation and cross-cultural adaptation of the non-English version of the OAB-q has been done successfully. This study showed the Korean OAB-q is associated with good psychometric properties in OAB subjects and demonstrated the usefulness of the Korean version of the OAB-q, an essential tool that can be utilized for international clinical trials and various clinical studies on OAB.
    In conclusion, the Korean version of the OAB-q is a valid and reliable instrument to measure outcomes in Korean patients with OAB.


    This research was funded by Pfizer Korea Ltd.


    No potential conflict of interest relevant to this article was reported.


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    Table 1
    Demographics of the 58 overactive bladder patients
    Item No. (%)
    Age (yr) 30-39 1 (1.7)
    40-49 7 (12.0)
    50-59 15 (25.8)
    60-69 24 (41.3)
    70-79 7 (12.0)
    80- 4 (6.9)
    Residence Seoul 37 (64.9)
    Busan 1 (1.7)
    Incheon 3 (5.2)
    Ulsan 1 (1.7)
    Gyeonggi-do province 13 (22.8)
    Jeollanam-do province 2 (3.5)
    History of genitourinary surgery Yes 6 (10.3)
    No 52 (89.6)
    History of surgerya) Hysterectomy 16 (27.5)
    Brain or spinal surgery 3 (5.1)
    Others 18 (31.0)
    No 21 (36.2)
    History of diseasea) Stroke 1 (1.7)
    Diabetes mellitus 14 (24.5)
    Brain or spinal injury 1 (1.7)
    Brain or spinal disease 1 (1.7)
    No 40 (70.1)
    Marital status Married and living with spouse 44 (78.5)
    Widowed 8 (14.2)
    Divorced 4 (7.1)
    Occupation Agriculture 1 (1.7)
    Service, merchant 3 (5.1)
    Professional, management 1 (1.7)
    Housewife 46 (79.3)
    No 7 (12.0)
    Level of education Elementary school 15 (25.8)
    Middle school 16 (27.5)
    High school 16 (27.5)
    College or higher 11 (18.9)
    Monthly income (Korean won) Less than 1.0 million 17 (29.3)
    1.0-1.9 million 9 (15.5)
    2.0-2.9 million 14 (24.1)
    Over 3.0 million 13 (22.4)
    No response 5 (8.6)

    a)Answer may have overlapped when the patient could select multiple responses.

    Table 2
    Face validity of the overactive bladder questionnaire (n=58)
    Item No. (%)
    Time taken to complete the questionnaire (min)
     7 1 (1.7)
     10 1 (1.7)
     15 9 (15.5)
     20 47 (81.0)
    Is each question simple and easy to understand ?
     Not at all 3 (5.1)
     A little 6 (10.3)
     Moderately 25 (43.1)
     Quite a bit 20 (34.4)
     Extremely 4 (6.9)
    Is questionnaire relevant to your condition ?
     Not at all 1 (1.7)
     A little 4 (6.9)
     Moderately 23 (39.6)
     Quite a bit 23 (39.6)
     Extremely 7 (12.0)
    Is each question clear and easy to understand ?
     Not at all 1 (1.7)
     A little 4 (6.9)
     Moderately 25 (43.1)
     Quite a bit 23 (39.6)
     Extremely 5 (8.6)
    Is the format of questionnaire easy to understand ?
     Not at all 1 (1.7)
     A little 5 (8.6)
     Moderately 23 (39.6)
     Quite a bit 22 (37.9)
     Extremely 7 (12.0)
    Table 3
    Discriminant validity
    Questionnaire Domain Control (n=58) Patient group (n=58) P-value
    OAB-q Symptom severity 12.2±12.0 46.9±20.3 <0.001
    Coping 91.4 ±12.2 59.7±25.1 <0.001
    Concern 92.7±8.1 66.6±22.2 <0.001
    Sleep 86.5±13.1 56.4±26.4 <0.001
    Social 95.3±10.2 76.4±25.6 <0.001
    HRQoL total 91.6±9.1 64.3±21.8 <0.001
    OAB-q SF Symptom severity 12.6±12.5 45.1±21.3 <0.001
    HRQoL total 91. 5±9.5 63.0±22.2 <0.001
    KHQ General health 49.1±20.9 65.5±23.3 <0.001
    Impact on life 39.6±30.8 71.8±24.8 <0.001
    Role limitations 10.9±18.3 57.1±32.7 <0.001
    Physical limitations 15.5±17.6 59.6±31.0 <0.001
    Social limitations 3.4±11.0 35.1±34.7 <0.001
    Personal relationships 10.4±18.2 31.7±31.3 0.003
    Emotions 8.6±16.1 50.0±32.3 <0.001
    Sleep/energy 13.2±15.8 46.5±29.9 <0.001
    Severity measures 10.3±10.0 34.4±28.2 <0.001
    SF-36 Physical functioning 76.3±21.2 55.5±30.0 <0.001
    Role-physical 77.2±22.9 60.1±31.2 0.004
    Pain 69.1±28.5 58.3±28.7 0.041
    General health 49.6±19.3 38.7±20.6 0.006
    Vitality 48.7±21.7 40.2±22.9 0.058
    Social functioning 80.3±20.9 71.3±24.2 0.041
    Role-emotional 77.8±24.7 63.3±31.1 0.014
    Mental health 64.5±20.8 58.0±22.3 0.204

    Values are presented as the mean±standard deviation and analyzed using Wilcoxon rank-sums test.

    OAB-q, overactive bladder questionnaire; HRQoL, health-related quality of life; OAB-q SF, overactive bladder questionnaire short form; KHQ, King's health questionnaire; SF-36, short-form 36.

    Table 4
    Convergent validity of the OAB-q
    No. Symptom severity Coping Concern Sleep Social HRQoL total Short form symptom severity Short form HRQoL total
     General health 58 0.226a) -0.288 -0.303 -0.439 -0.366 -0.410 0.238a) -0.347
     Impact on Life 58 0.628 -0.603 -0.648 -0.508 -0.400 -0.646 0.590 -0.656
     Role limitations 58 0.649 -0.650 -0.498 -0.533 -0.543 -0.679 0.609 -0.670
     Physical limitations 57 0.611 -0.628 -0.614 -0.638 -0.509 -0.723 0.565 -0.738
     Social limitations 58 0.511 -0.605 -0.650 -0.617 -0.604 -0.741 0.520 -0.740
     Personal relationships 41 0.250a) -0.190a) -0.363 -0.198a) -0.405 -0.314 0.249a) -0.272a)
     Emotions 58 0.404 -0.475 -0.606 -0.338 -0.479 -0.554 0.368 -0.552
     Sleep/energy 58 0.634 -0.604 -0.655 -0.807 -0.445 -0.721 0.647 -0.743
     Severity measures 58 0.367 -0.476 -0.499 -0.349 -0.442 -0.543 0.392 -0.520
     Physical functioning 58 -0.261 0.322 0.304 0.324 0.243a) 0.371 -0.298 0.325
     Role-physical 58 -0.159a) 0.356 0.418 0.340 0.267 0.409 -0.216a) 0.388
     Pain 58 -0.100a) 0.124a) 0.051a) 0.239a) 0.079a) 0.144a) -0.065a) 0.095a)
     General health 58 -0.153a) 0.115a) 0.217a) 0.289 0.162a) 0.235a) -0.218a) 0.193a)
     Vitality 57 -0.153a) 0.180a) 0.239a) 0.324 0.161a) 0.253a) -0.151a) 0.238a)
     Social functioning 58 -0.147a) 0.218a) 0.282 0.217a) 0.326 0.319 -0.190a) 0.285
     Role-emotional 58 -0.210a) 0.330 0.295 0.272 0.152a) 0.343 -0.248a) 0.331
     Mental health 57 0.006a) -0.050a) 0.145a) 0.134a) 0.114a) 0.054a) -0.010a) 0.006a)

    OAB-q, overactive bladder questionnaire; HRQoL, health-related quality of life; KHQ, King's health questionnaire; SF-36, short-form 36.

    a)Spearman's correlations coefficients is not significant at α=0.05.

    Table 5
    Internal consistency of the OAB-q at the first visit (n=58)
    Questionnaire Domain No. of items Cronbach’s α
    OAB-q Symptom severity 8 0.82
    Coping 8 0.87
    Concern 7 0.87
    Sleep 5 0.86
    Social 5 0.86
    HRQoL total 33 0.95
    OAB-q SF Symptom severity 6 0.77
    HRQoL total 13 0.90

    OAB-q, overactive bladder questionnaire; HRQoL, health-related quality of life; OAB-q SF, overactive bladder questionnaire short form.

    Table 6
    Reproducibility of the OAB-q data
    Question- naire Domain or item Intra-class correlation coefficient Spearman’s correlations
    OAB-q Symptom severity 0.67 (0.445, 0.820) 0.65b)
    Coping 0.66 (0.434, 0.816) 0.63b)
    Concern 0.61(0.360, 0.784) 0.60b)
    Sleep 0.77 (0.607, 0.881) 0.78b)
    Social 0.55 (0.272, 0.743) 0.59b)
    HRQoL total 0.69 (0.471, 0.831) 0.69b)
    OAB-q SF Symptom severity 0.67 (0.452, 0.823) 0.66b)
    HRQoL total 0.71 (0.511, 0.846) 0.73b)
    1 0.49 (0.200, 0.707) 0.47a)
    2 0.42 (0.109, 0.657) 0.35a)
    3 0.44 (0.143, 0.676) 0.40a)
    4 0.52 (0.245, 0.730) 0.55b)
    5 0.75 (0.568, 0.867) 0.77b)
    6 0.85 (0.728, 0.922) 0.84b)
    7 0.36 (0.040, 0.616) 0.37a)
    8 0.50 (0.215, 0.715) 0.51a)
    9 0.46 (0.163, 0.687) 0.40a)
    10 0.51 (0.228, 0.721) 0.50a)
    11 0.38 (0.068, 0.633) 0.35a)
    12 0.52 (0.237, 0.726) 0.51a)
    13 0.54 (0.262, 0.738) 0.54b)
    14 0.30 (-0.025, 0.574) 0.21
    15 0.67 (0.447, 0.821) 0.67b)
    16 0.38 (0.069, 0.634) 0.40a)
    17 0.36 (0.044, 0.619) 0.38a)
    18 0.47 (0.176, 0.694) 0.57b)
    19 0.49 (0.201, 0.708) 0.52a)
    20 0.65 (0.413, 0.807) 0.68b)
    21 0.57 (0.301, 0.757) 0.52a)
    22 0.58 (0.315, 0.763) 0.56b)
    23 0.73 (0.542, 0.858) 0.62b)
    24 0.85 (0.733, 0.924) 0.86b)
    25 0.35 (0.028, 0.609) 0.56b)
    26 0.59 (0.336, 0.773) 0.58b)
    27 0.28 (-0.047, 0.559) 0.37a)
    28 0.60 (0.348, 0.778) 0.72b)
    29 0.19 (-0.143, 0.489) 0.63b)
    30 0.65 (0.413, 0.807) 0.67b)
    31 0.15 (-0.185, 0.456) 0.32
    32 0.30 (-0.026, 0.574) 0.32
    33 0.64 (0.410, 0.805) 0.65b)

    Differences in scores from the first and second visits (n=35).

    OAB-q, overactive bladder questionnaire; HRQoL, health-related quality of life; OAB-q SF, overactive bladder questionnaire short form.

    a)P<0.05. b)P<0.001.

    Table 7
    Changes in scores before and after treatment, effect size and standardized response mean for the OAB-q scales
    No. Mean SD P-value Effect size Standardized response mean
    Δ OAB-qa) Symptom severity 27 -24.8 16.0 <0.001 -1.48 -1.55
    Coping 27 19.3 20.3 <0.001 0.91 0.95
    Concern 27 14.7 23.0 0.001 0.86 0.64
    Sleep 27 17.0 23.3 <0.001 0.88 0.73
    Social 27 7.4 20.4 0.059 0.57 0.36
    HRQoL total 27 15.2 19.5 <0.001 0.89 0.78
    Δ OAB-q SFa) Symptom severity 27 -21.8 16.9 <0.001 -1.24 -1.29
    HRQoL total 27 16.6 18.8 <0.001 1.04 0.88

    OAB-q, overactive bladder questionnaire; HRQoL, health-related quality of life; OAB-q SF, overactive bladder questionnaire short form.

    a)Differences in scores from the first and second visits, Wilcoxon signed rank test.

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